Scaling up interventions to achieve global tuberculosis control: progress and new developments
Identifieur interne : 005934 ( Main/Exploration ); précédent : 005933; suivant : 005935Scaling up interventions to achieve global tuberculosis control: progress and new developments
Auteurs : Mario Raviglione [Suisse] ; Ben Marais [Australie] ; Katherine Floyd [Suisse] ; Knut Lönnroth [Suisse] ; Haileyesus Getahun [Suisse] ; Giovanni B. Migliori [Italie] ; Anthony D. Harries [France, Royaume-Uni] ; Paul Nunn [Suisse] ; Christian Lienhardt Steve Graham [Suisse, Australie] ; Jeremiah Chakaya [Kenya] ; Karin Weyer [Suisse] ; Stewart Cole [Suisse] ; Stefan H. E. Kaufmann [Allemagne] ; Alimuddin Zumla [Royaume-Uni, Zambie]Source :
- Lancet : (British edition) [ 0140-6736 ] ; 2012.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Innovation, Médecine.
English descriptors
- KwdEn :
Abstract
Tuberculosis is still one of the most important causes of death worldwide. The 2010 Lancet tuberculosis series provided a comprehensive overview of global control efforts and challenges. In this update we review recent progress. With improved control efforts, the world and most regions are on track to achieve the Millennium Development Goal of decreasing tuberculosis incidence by 2015, and the Stop TB Partnership target of halving 1990 mortality rates by 2015; the exception is Africa. Despite these advances, full scale-up of tuberculosis and HIV collaborative activities remains challenging and emerging drug-resistant tuberculosis is a major threat. Recognition of the effect that non-communicable diseases-such as smoking-related lung disease, diet-related diabetes mellitus, and alcohol and drug misuse-have on individual vulnerability, as well as the contribution of poor living conditions to community vulnerability, shows the need for multidisciplinary approaches. Several new diagnostic tests are being introduced in endemic countries and for the first time in 40 years a coordinated portfolio of promising new tuberculosis drugs exists. However, none of these advances offer easy solutions. Achievement of international tuberculosis control targets and maintenance of these gains needs optimum national health policies and services, with ongoing investment into new approaches and strategies. Despite growing funding in recent years, a serious shortfall persists. International and national financial uncertainty places gains at serious risk. Perseverance and renewed commitment are needed to achieve global control of tuberculosis, and ultimately, its elimination.
Affiliations:
- Allemagne, Australie, France, Italie, Kenya, Royaume-Uni, Suisse, Zambie
- Angleterre, Berlin, Canton de Vaud, Grand Londres, Nouvelle-Galles du Sud, Victoria (État), Île-de-France
- Berlin, Lausanne, Londres, Melbourne, Paris, Sydney
- University College de Londres, Université de Melbourne, Université de Sydney
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Migliori</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>WHO Collaborating Centre forTB and Lung Diseases, Fondazione S Maugeri, Care and Research Institute</s1><s2>Tradate</s2><s3>ITA</s3><sZ>6 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Tradate</wicri:noRegion></affiliation></author><author><name sortKey="Harries, Anthony D" sort="Harries, Anthony D" uniqKey="Harries A" first="Anthony D." last="Harries">Anthony D. 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Kaufmann</name><affiliation wicri:level="3"><inist:fA14 i1="10"><s1>Max Planck Institute for Infection Biology</s1><s2>Berlin</s2><s3>DEU</s3><sZ>13 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Zumla, Alimuddin" sort="Zumla, Alimuddin" uniqKey="Zumla A" first="Alimuddin" last="Zumla">Alimuddin Zumla</name><affiliation wicri:level="4"><inist:fA14 i1="11"><s1>Department of Infection, Division of Infection and Immunity, University College London</s1><s2>London</s2><s3>GBR</s3><sZ>14 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="12"><s1>University of Zambia-University College London Medical School Research and Training Project, University Teaching Hospital</s1><s2>Lusaka</s2><s3>ZMB</s3><sZ>14 aut.</sZ></inist:fA14><country>Zambie</country><wicri:noRegion>Lusaka</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">12-0228983</idno><date when="2012">2012</date><idno type="stanalyst">PASCAL 12-0228983 INIST</idno><idno type="RBID">Pascal:12-0228983</idno><idno type="wicri:Area/PascalFrancis/Corpus">001354</idno><idno type="wicri:Area/PascalFrancis/Curation">004B61</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000D86</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000D86</idno><idno type="wicri:doubleKey">0140-6736:2012:Raviglione M:scaling:up:interventions</idno><idno type="wicri:Area/Main/Merge">005C21</idno><idno type="wicri:Area/Main/Curation">005934</idno><idno type="wicri:Area/Main/Exploration">005934</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Scaling up interventions to achieve global tuberculosis control: progress and new developments</title><author><name sortKey="Raviglione, Mario" sort="Raviglione, Mario" uniqKey="Raviglione M" first="Mario" last="Raviglione">Mario Raviglione</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>STOPTB Department, WHO</s1><s2>Geneva</s2><s3>CHE</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author><author><name sortKey="Marais, Ben" sort="Marais, Ben" uniqKey="Marais B" first="Ben" last="Marais">Ben Marais</name><affiliation wicri:level="4"><inist:fA14 i1="02"><s1>Sydney Institute for Emerging Infectious Diseases and Biosecurity and The Children's Hospital at Westmead, Sydney Medical School, University of Sydney</s1><s2>Sydney</s2><s3>AUS</s3><sZ>2 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region><settlement type="city">Sydney</settlement></placeName><orgName type="university">Université de Sydney</orgName></affiliation></author><author><name sortKey="Floyd, Katherine" sort="Floyd, Katherine" uniqKey="Floyd K" first="Katherine" last="Floyd">Katherine Floyd</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>STOPTB Department, WHO</s1><s2>Geneva</s2><s3>CHE</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author><author><name sortKey="Lonnroth, Knut" sort="Lonnroth, Knut" uniqKey="Lonnroth K" first="Knut" last="Lönnroth">Knut Lönnroth</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>STOPTB Department, WHO</s1><s2>Geneva</s2><s3>CHE</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author><author><name sortKey="Getahun, Haileyesus" sort="Getahun, Haileyesus" uniqKey="Getahun H" first="Haileyesus" last="Getahun">Haileyesus Getahun</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>STOPTB Department, WHO</s1><s2>Geneva</s2><s3>CHE</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author><author><name sortKey="Migliori, Giovanni B" sort="Migliori, Giovanni B" uniqKey="Migliori G" first="Giovanni B." last="Migliori">Giovanni B. Migliori</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>WHO Collaborating Centre forTB and Lung Diseases, Fondazione S Maugeri, Care and Research Institute</s1><s2>Tradate</s2><s3>ITA</s3><sZ>6 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Tradate</wicri:noRegion></affiliation></author><author><name sortKey="Harries, Anthony D" sort="Harries, Anthony D" uniqKey="Harries A" first="Anthony D." last="Harries">Anthony D. Harries</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>International Union Against Tuberculosis and Lung Disease</s1><s2>Paris</s2><s3>FRA</s3><sZ>7 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>London School of Hygiene and Tropical Medicine</s1><s2>London</s2><s3>GBR</s3><sZ>7 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Nunn, Paul" sort="Nunn, Paul" uniqKey="Nunn P" first="Paul" last="Nunn">Paul Nunn</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>STOPTB Department, WHO</s1><s2>Geneva</s2><s3>CHE</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author><author><name sortKey="Graham, Christian Lienhardt Steve" sort="Graham, Christian Lienhardt Steve" uniqKey="Graham C" first="Christian Lienhardt Steve" last="Graham">Christian Lienhardt Steve Graham</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>STOPTB Department, WHO</s1><s2>Geneva</s2><s3>CHE</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Geneva</wicri:noRegion></affiliation><affiliation wicri:level="4"><inist:fA14 i1="06"><s1>Centre for International Child Health, University of Melbourne</s1><s2>Melbourne</s2><s3>AUS</s3><sZ>9 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="07"><s1>Murdoch Children's Research Institute, Royal Children's Hospital</s1><s2>Melbourne</s2><s3>AUS</s3><sZ>9 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Chakaya, Jeremiah" sort="Chakaya, Jeremiah" uniqKey="Chakaya J" first="Jeremiah" last="Chakaya">Jeremiah Chakaya</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Centre for Respiratory Diseases Research, Kenya Medical Research Institute</s1><s2>Nairobi</s2><s3>KEN</s3><sZ>10 aut.</sZ></inist:fA14><country>Kenya</country><wicri:noRegion>Nairobi</wicri:noRegion></affiliation></author><author><name sortKey="Weyer, Karin" sort="Weyer, Karin" uniqKey="Weyer K" first="Karin" last="Weyer">Karin Weyer</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>STOPTB Department, WHO</s1><s2>Geneva</s2><s3>CHE</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author><author><name sortKey="Cole, Stewart" sort="Cole, Stewart" uniqKey="Cole S" first="Stewart" last="Cole">Stewart Cole</name><affiliation wicri:level="3"><inist:fA14 i1="09"><s1>Global Health Institute, Ecole Polytechnique Fédérale de Lausanne</s1><s2>Lausanne</s2><s3>CHE</s3><sZ>12 aut.</sZ></inist:fA14><country>Suisse</country><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Kaufmann, Stefan H E" sort="Kaufmann, Stefan H E" uniqKey="Kaufmann S" first="Stefan H. E." last="Kaufmann">Stefan H. E. Kaufmann</name><affiliation wicri:level="3"><inist:fA14 i1="10"><s1>Max Planck Institute for Infection Biology</s1><s2>Berlin</s2><s3>DEU</s3><sZ>13 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Zumla, Alimuddin" sort="Zumla, Alimuddin" uniqKey="Zumla A" first="Alimuddin" last="Zumla">Alimuddin Zumla</name><affiliation wicri:level="4"><inist:fA14 i1="11"><s1>Department of Infection, Division of Infection and Immunity, University College London</s1><s2>London</s2><s3>GBR</s3><sZ>14 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="12"><s1>University of Zambia-University College London Medical School Research and Training Project, University Teaching Hospital</s1><s2>Lusaka</s2><s3>ZMB</s3><sZ>14 aut.</sZ></inist:fA14><country>Zambie</country><wicri:noRegion>Lusaka</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Lancet : (British edition)</title><title level="j" type="abbreviated">Lancet : (Br. ed.)</title><idno type="ISSN">0140-6736</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Lancet : (British edition)</title><title level="j" type="abbreviated">Lancet : (Br. ed.)</title><idno type="ISSN">0140-6736</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Development</term><term>Innovation</term><term>Medicine</term><term>Sanitary surveillance</term><term>Tuberculosis</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Tuberculose</term><term>Innovation</term><term>Surveillance sanitaire</term><term>Développement</term><term>Médecine</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Innovation</term><term>Médecine</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Tuberculosis is still one of the most important causes of death worldwide. The 2010 Lancet tuberculosis series provided a comprehensive overview of global control efforts and challenges. In this update we review recent progress. With improved control efforts, the world and most regions are on track to achieve the Millennium Development Goal of decreasing tuberculosis incidence by 2015, and the Stop TB Partnership target of halving 1990 mortality rates by 2015; the exception is Africa. Despite these advances, full scale-up of tuberculosis and HIV collaborative activities remains challenging and emerging drug-resistant tuberculosis is a major threat. Recognition of the effect that non-communicable diseases-such as smoking-related lung disease, diet-related diabetes mellitus, and alcohol and drug misuse-have on individual vulnerability, as well as the contribution of poor living conditions to community vulnerability, shows the need for multidisciplinary approaches. Several new diagnostic tests are being introduced in endemic countries and for the first time in 40 years a coordinated portfolio of promising new tuberculosis drugs exists. However, none of these advances offer easy solutions. Achievement of international tuberculosis control targets and maintenance of these gains needs optimum national health policies and services, with ongoing investment into new approaches and strategies. Despite growing funding in recent years, a serious shortfall persists. International and national financial uncertainty places gains at serious risk. Perseverance and renewed commitment are needed to achieve global control of tuberculosis, and ultimately, its elimination.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>France</li><li>Italie</li><li>Kenya</li><li>Royaume-Uni</li><li>Suisse</li><li>Zambie</li></country><region><li>Angleterre</li><li>Berlin</li><li>Canton de Vaud</li><li>Grand Londres</li><li>Nouvelle-Galles du Sud</li><li>Victoria (État)</li><li>Île-de-France</li></region><settlement><li>Berlin</li><li>Lausanne</li><li>Londres</li><li>Melbourne</li><li>Paris</li><li>Sydney</li></settlement><orgName><li>University College de Londres</li><li>Université de Melbourne</li><li>Université de Sydney</li></orgName></list><tree><country name="Suisse"><noRegion><name sortKey="Raviglione, Mario" sort="Raviglione, Mario" uniqKey="Raviglione M" first="Mario" last="Raviglione">Mario Raviglione</name></noRegion><name sortKey="Cole, Stewart" sort="Cole, Stewart" uniqKey="Cole S" first="Stewart" last="Cole">Stewart Cole</name><name sortKey="Floyd, Katherine" sort="Floyd, Katherine" uniqKey="Floyd K" first="Katherine" last="Floyd">Katherine Floyd</name><name sortKey="Getahun, Haileyesus" sort="Getahun, Haileyesus" uniqKey="Getahun H" first="Haileyesus" last="Getahun">Haileyesus Getahun</name><name sortKey="Graham, Christian Lienhardt Steve" sort="Graham, Christian Lienhardt Steve" uniqKey="Graham C" first="Christian Lienhardt Steve" last="Graham">Christian Lienhardt Steve Graham</name><name sortKey="Lonnroth, Knut" sort="Lonnroth, Knut" uniqKey="Lonnroth K" first="Knut" last="Lönnroth">Knut Lönnroth</name><name sortKey="Nunn, Paul" sort="Nunn, Paul" uniqKey="Nunn P" first="Paul" last="Nunn">Paul Nunn</name><name sortKey="Weyer, Karin" sort="Weyer, Karin" uniqKey="Weyer K" first="Karin" last="Weyer">Karin Weyer</name></country><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Marais, Ben" sort="Marais, Ben" uniqKey="Marais B" first="Ben" last="Marais">Ben Marais</name></region><name sortKey="Graham, Christian Lienhardt Steve" sort="Graham, Christian Lienhardt Steve" uniqKey="Graham C" first="Christian Lienhardt Steve" last="Graham">Christian Lienhardt Steve Graham</name><name sortKey="Graham, Christian Lienhardt Steve" sort="Graham, Christian Lienhardt Steve" uniqKey="Graham C" first="Christian Lienhardt Steve" last="Graham">Christian Lienhardt Steve Graham</name></country><country name="Italie"><noRegion><name sortKey="Migliori, Giovanni B" sort="Migliori, Giovanni B" uniqKey="Migliori G" first="Giovanni B." last="Migliori">Giovanni B. Migliori</name></noRegion></country><country name="France"><region name="Île-de-France"><name sortKey="Harries, Anthony D" sort="Harries, Anthony D" uniqKey="Harries A" first="Anthony D." last="Harries">Anthony D. Harries</name></region></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Harries, Anthony D" sort="Harries, Anthony D" uniqKey="Harries A" first="Anthony D." last="Harries">Anthony D. Harries</name></region><name sortKey="Zumla, Alimuddin" sort="Zumla, Alimuddin" uniqKey="Zumla A" first="Alimuddin" last="Zumla">Alimuddin Zumla</name></country><country name="Kenya"><noRegion><name sortKey="Chakaya, Jeremiah" sort="Chakaya, Jeremiah" uniqKey="Chakaya J" first="Jeremiah" last="Chakaya">Jeremiah Chakaya</name></noRegion></country><country name="Allemagne"><region name="Berlin"><name sortKey="Kaufmann, Stefan H E" sort="Kaufmann, Stefan H E" uniqKey="Kaufmann S" first="Stefan H. E." last="Kaufmann">Stefan H. E. Kaufmann</name></region></country><country name="Zambie"><noRegion><name sortKey="Zumla, Alimuddin" sort="Zumla, Alimuddin" uniqKey="Zumla A" first="Alimuddin" last="Zumla">Alimuddin Zumla</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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